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An analysis platform to:

• identify and characterize the determinants of grape and wine quality
• search, identify and characterize defense metabolites in grapevine 
• carry out targeted or global metabolomic analyses in collaboration with national and international scientific partners

The equipment:

• two gas chromatographs coupled to mass spectrometers and equipped with automatic injector/samplers, dedicated to the analysis of volatile metabolites. One of the instruments is equipped with an olfactometric detector for characterizing grape and wine aromas. The olfactometric technique uses the human nose as a sensory detector, complementing mass spectrometry, to identify and characterize odorous molecules.
• a Thermo Vanquish UHPLC liquid chromatography chain coupled to a Thermo Exploris 120 high-resolution mass spectrometer (Orbitrap technology) for the analysis of non-volatile compounds.

The equipment for this platform was acquired with funding from INRAE (CNOC and BAP department), the University of Strasbourg, the Institut de Biologie Moléculaire des Plantes (IBMP), the Agence Nationale de la Recherche (ANR), the Comité National des Interprofessions des Vins à Appellation d'Origine (CNIV), Colmar Agglomération, the Région Grand Est and the European Union.

Recent publications

• Olazcuaga, L. et al. Metabolic consequences of various fruit-based diets in a generalist insect species. eLife 12, e84370 (2023). https://doi.org/10.7554/elife.84370
• Platel, R. et al. Deciphering immune responses primed by a bacterial lipopeptide in wheat towards Zymoseptoria tritici. Frontiers in Plant Science 13, 1074447 (2023). https://doi.org/10.3389/fpls.2022.1074447
• Koutouan, C., Emmanuel et al. Co-Localization of Resistance and Metabolic Quantitative Trait Loci on Carrot Genome Reveals Fungitoxic Terpenes and Related Candidate Genes Associated with the Resistance to Alternaria dauci. Metabolites 13, 71 (2023).
• Flubacher, N. et al. The fungal metabolite 4‐hydroxyphenylacetic acid from Neofusicoccum parvum modulates defence responses in grapevine. Plant, Cell and Environment (2023). https://doi.org/10.1111/pce.14670
• Rodrigues, M. et al. (2023) Metabolic and Molecular Rearrangements of Sauvignon Blanc (Vitis vinifera L.) Berries in Response to Foliar Applications of Specific Dry Yeast. Plants,12,3423. https://doi.org/10.3390/plants12193423
• Allario, T. et al. Analysis of defense-related gene expression and leaf metabolome in wheat during the early infection stages of Blumeria graminis f.sp. tritici. Phytopathology (2023). https://doi.org/10.1094/PHYTO-10-22-0364-R
• Schilling, M. et al. Wood degradation by Fomitiporia mediterranea M. Fischer: Physiologic, metabolomic and proteomic approaches. Frontiers in Plant Science 13, 988709 (2022). https://doi.org/10.3389/fpls.2022.988709
• Platel, R. et al. Bioinspired Rhamnolipid Protects Wheat Against Zymoseptoria tritici Through Mainly Direct Antifungal Activity and Without Major Impact on Leaf Physiology. Frontiers in Plant Science 13, 878272 (2022). https://doi.org/10.3389/fpls.2022.878272
• Negrel, L. et al. Comparative Metabolomic Analysis of Four Fabaceae and Relationship to In Vitro Nematicidal Activity against Xiphinema index. Molecules 27, 3052 (2022). https://doi.org/10.3390/molecules27103052
• Koschmieder, J. et al. Color recycling: metabolization of apocarotenoid degradation products suggests carbon regeneration via primary metabolic pathways. Plant Cell Reports 41, 961 - 977 (2022). https://doi.org/10.1007/s00299-022-02831-8
• de Borba, M. et al. A Laminarin-Based Formulation Protects Wheat Against Zymoseptoria tritici via Direct Antifungal Activity and Elicitation of Host Defense-Related Genes. Plant Disease 106, 1408-1418 (2022). https://doi.org/10.1094/pdis-08-21-1675-re